GLI1 Protein, Human, Recombinant (His)

TargetMol Chemicals

GLI1 Protein, Human, Recombinant (His)

16

Research Use Only

23.3 kDa (predicted)

Acts as a transcriptional activator. Binds to the DNA consensus sequence 5-GACCACCCA-3. Regulates the transcription of specific genes during normal development. Plays a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling. Plays a role in cell proliferation and differentiation via its role in SHH signaling.; Acts as a transcriptional activator, but activates a different set of genes than isoform 1. Activates expression of CD24, unlike isoform 1. Mediates SHH signaling. Promotes cancer cell migration.

-20°C

12352200