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ProductsBack/Globosuxanthone A [917091-74-8]
Chemical Structure
Chemical Structure
Chemical Structure

Globosuxanthone A [917091-74-8]

Research Use Only
AG-CN2-0174
AdipoGen Life Sciences
CAS Number917091-74-8
DownloadMSDS
Product group Chemicals
Estimated Purity>95%
Molecular Weight304.3
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Globosuxanthone A [917091-74-8]
  • Delivery Days Customer
    10
  • CAS Number
    917091-74-8
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Hazard Information
    Warning
  • Molecular Formula
    C15H12O7
  • Molecular Weight
    304.3
  • Scientific Description
    Chemical. CAS: 917091-74-8. Formula: C15H12O7. MW: 304.3. Isolated from fungus (species unknown). Potent anticancer agent. Inhibits cell growth, proliferation and survival of human tumor cells lines in vivo and in vitro. Exhibits strong cytotoxicity against a panel of human solid tumor cell lines, disrupting the cell cycle leading to the accumulation of cells in either G2/M or S phase and inducing classic signs of apoptosis. Antifungal agent against Candida albicans. - Potent anticancer agent. Inhibits cell growth, proliferation and survival of human tumor cells lines in vivo and in vitro. Exhibits strong cytotoxicity against a panel of human solid tumor cell lines, disrupting the cell cycle leading to the accumulation of cells in either G2/M or S phase and inducing classic signs of apoptosis. Antifungal agent against Candida albicans.
  • SMILES
    OC1=C2C(OC(C=C[C@@H](O)[C@]3(C(OC)=O)O)=C3C2=O)=CC=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • A new dihydroxanthenone from a plant-associated strain of the fungus Chaetomium globosum demonstrates anticancer activity: E.M.K.Wijeratne, et al.; Bioorg. Med. Chem. 14, 7917 (2006)
  • Absolute Configurations of Globosuxanthone A and Secondary Metabolites from Microdiplodia sp.- A Novel Solid-State CD/TDDFT Approach: H. Hussain, et al.; Eur. J. Org. Chem. 2007, 292 (2007)
  • A new dibenz[b,e]oxepine derivative, 1-hydroxy-10-methoxy-dibenz[b,e]oxepin-6,11-dione, from a marine-derived fungus, Beauveria bassiana TPU942; H. Yamazaki, et al.; Mar. Drugs 10, 2691 (2012)
  • Dihydroxanthenones from the fermentation product of an endophytic fungus Gliomastix murorum: H.Y. Yang, et al.; J. Asian Nat. Prod. Res. 17, 319 (2015)