Glucocorticoid receptor agonist [1245526-82-2]

MedChem Express

Glucocorticoid receptor agonist [1245526-82-2]

10

1245526-82-2

Research Use Only

99.06

C20H20F4N2O2

396.38

Glucocorticoid receptor agonist is a Glucocorticoid receptor agonist that acts on Glucocorticoid receptor (GR), progesterone receptor (PR) and mineralocorticoid receptor (MR) with the IC50 values of 2.1 , 1200 and 210 nM, respectively. Glucocorticoid receptor agonist has steroid-like anti-inflammatory properties and may be used to improve metabolism and reduce increased levels of body fat and serum insulin[1].

OC1=CC=C(C=C1C(C)(C[C@](O)(C(F)(F)F)CC2=CC3=C(C=NC=C3)N2)C)F

-20°C,2°C to 8°C

12352200