GLUD1 Polyclonal Antibody

Reddot Biotech

GLUD1 Polyclonal Antibody

5

ImmunoFluorescence, ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

GLUD1

glutamate dehydrogenase 1

epididymis secretory sperm binding protein; epididymis tissue sperm binding protein Li 18mP; GDH; GDH1; GLUD; glutamate dehydrogenase (NAD(P)+); glutamate dehydrogenase 1, mitochondrial

Rabbit

IgG

This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.

Human, Mouse, Rat

-20°C

12352203