GLUT1/EGFR-IN-1 [2393787-80-7]

TargetMol Chemicals

GLUT1/EGFR-IN-1 [2393787-80-7]

9

Research Use Only

C44H32N4O5

696.75

GLUT1/EGFR-IN-1 (compound H) is a potent inhibitor of both GLUT1 and EGFR. It targets the ATP-binding site of the EGFR tyrosine kinase and inhibits GLUT1-mediated energy metabolism, resulting in reduced ATP, MMP, intracellular lactate, and nuclear translocation of EGFR. GLUT1/EGFR-IN-1 is applicable in the research of nasopharyngeal carcinoma (NPC) and triple-negative breast cancer (TNBC).

O=C(NC=1C=CC2=NC=NC(NC3=CC=C(C=C3)C)=C2C1)C4=CC(OCC=5C=CC=CC5)=C6C(=O)C=7C(OCC=8C=CC=CC8)=CC=CC7C(=O)C6=C4

-20°C

51202000