Glutaminase C (GAC) antibody [GT1075]

GeneTex

Glutaminase C (GAC) antibody [GT1075]

9

Specific for GAC but not KGA isoform

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

GT1075

1 mg/ml

Unconjugated

Liquid

GLS

glutaminase

AAD20; CASGID; DEE71; EIEE71; GAC; GAM; GDPAG; GLS1; glutaminase C; glutaminase kidney isoform, mitochondrial; glutaminase, phosphate-activated; KGA; K-glutaminase; L-glutamine amidohydrolase

Mouse

IgG2b

Glutaminase kidney isoform, mitochondrial

Sahai (1983) [PubMed 6825316] demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter (Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) [PubMed 6682827] who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.[supplied by OMIM]

Human

-20°C or -80°C,2°C to 8°C

12352203