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ProductsBack/Glyburide-d3 [1219803-02-7]

Glyburide-d3 [1219803-02-7]

HY-15206S1
MedChem Express
CAS Number1219803-02-7
DownloadMSDS
Product group Chemicals
Estimated Purity99.64
Molecular Weight497.02
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Glyburide-d3 [1219803-02-7]
  • Delivery Days Customer
    10
  • CAS Number
    1219803-02-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.64
  • Molecular Formula
    C23H25D3ClN3O5S
  • Molecular Weight
    497.02
  • Scientific Description
    Glyburide-d3 is the deuterium labeled Glibenclamide. Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity[1]. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR)[3]. Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability[4]. Glibenclamide can induce autophagy[5].
  • SMILES
    O=C(NCCC1=CC=C(S(=O)(NC(NC2CCCCC2)=O)=O)C=C1)C3=CC(Cl)=CC=C3OC([2H])([2H])[2H]
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12131703