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Glycine Receptor alpha 2 antibody

Name: Glycine Receptor alpha 2 antibody
SKU: GTX105634_G10
Availability: BackOrder

GTX105634

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Mouse

TargetGLRA2

Overview

Supplier
GeneTex
Product Name
Glycine Receptor alpha 2 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID2742
Target name
GLRA2
Target description
glycine receptor alpha 2
Target synonyms
GLR, MRXSP, glycine receptor subunit alpha-2, glycine receptor alpha 2 subunit, glycine receptor, alpha-2 polypeptide
Host
Rabbit
Isotype
IgG
Protein IDP23416
Protein Name
Glycine receptor subunit alpha-2
Scientific Description
The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encoding different isoforms have been found for this gene.
Reactivity
Human, Mouse
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Kuhse J, Groeneweg F, Kins S, et al. Loss of Extrasynaptic Inhibitory Glycine Receptors in the Hippocampus of an AD Mouse Model Is Restored by Treatment with Artesunate. Int J Mol Sci. 2023,24(5). doi: 10.3390/ijms24054623
Read this paper
Zhu H, Gouaux E. Architecture and assembly mechanism of native glycine receptors. Nature. 2021,599(7885):513-517. doi: 10.1038/s41586-021-04022-z
Read this paper
Puri J, Bellinger LL, Kramer PR. Estrogen in cycling rats alters gene expression in the temporomandibular joint, trigeminal ganglia and trigeminal subnucleus caudalis/upper cervical cord junction. J Cell Physiol. 2011,226(12):3169-80. doi: 10.1002/jcp.22671
Read this paper