Bio-Connect

GM2A Polyclonal Antibody

RD267777A
Reddot Biotech
ApplicationsWestern Blot
Product group Antibodies
ReactivityMouse, Rat
TargetGM2A
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    GM2A Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2760
  • Target name
    GM2A
  • Target description
    GM2 ganglioside activator
  • Target synonyms
    cerebroside sulfate activator protein; ganglioside GM2 activator; GM2-AP; SAP-3; shingolipid activator protein 3; sphingolipid activator protein 3
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
  • Reactivity
    Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203