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GNA002 [1385035-79-9]

GNA002 [1385035-79-9]

Research Use Only
T11436
TargetMol Chemicals
CAS Number1385035-79-9
DownloadMSDS
Product group Chemicals
Molecular Weight701.89
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    GNA002 [1385035-79-9]
  • Delivery Days Customer
    72
  • CAS Number
    1385035-79-9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    GNA002
  • Molecular Formula
    C42H55NO8
  • Molecular Weight
    701.89
  • Scientific Description
    GNA002 is a highly potent, specific, and covalent EZH2 (Enhancer of zeste homolog 2) inhibitor with an IC50 of 1.1 microM.
  • Shelf life instruction
    3 years
  • SMILES
    [H][C@@]12C[C@@]3([H])C=C4C(=O)c5c(O)c(C\C=C(/C)CCC=C(C)C)c(O)c(CC=C(C)C)c5O[C@@]14[C@@](C\C=C(\C)C(=O)NCCOCC)(OC2(C)C)C3=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination. Wang X et al., 2017 May 2, EMBO J
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