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ProductsBack/GNE-375 [1926989-06-1]
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GNE-375 [1926989-06-1]

Research Use Only
T27423
TargetMol Chemicals
Molecular Weight451.51
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Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    GNE-375 [1926989-06-1]
  • Delivery Days Customer
    4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    GNE-375
  • Molecular Formula
    C25H29N3O5
  • Molecular Weight
    451.51
  • Scientific Description
    GNE-375 is a selective and potent BRD9 inhibitor (IC50: 5 nM).GNE-375 inhibits BRD4, TAF1, and CECR2, and can be used to study epigenetic resistance.
  • Shelf life instruction
    3 years
  • SMILES
    COc1cc(c(OC)cc1C(=O)N1CCOCC1)-c1cn(C\C=C\C)c(=O)c2[nH]c(C)cc12
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Terry D Crawford, et al. Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3534-3541.
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