GNE-4997 [1705602-02-3]

TargetMol Chemicals

GNE-4997 [1705602-02-3]

999

1705602-02-3

Chemical

Research Use Only

GNE-4997

C25H27F2N5O3S

515.58

GNE-4997 is a potent and selective inhibitor of the interleukin-2-inducible T-cell kinase (Ki: 0.09 nM). The correlation between the basicity of solubilizing elements in GNE-4997 and off-target antiproliferative effects reduces cytotoxicity.

3 years

C[C@@]12[C@@](C1(F)F)(CC3=C(C2)NN=C3C(NC4=CN([C@@H]([C@@]5(S(=O)(=O)CCCC5)[H])C6=CC=CC=C6)N=C4)=O)[H]

-20°C

12352200