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ProductsBack/GNE-955 [1527523-39-2]
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GNE-955 [1527523-39-2]

Research Use Only
T15406
TargetMol Chemicals
CAS Number1527523-39-2
DownloadMSDS
Product group Chemicals
Molecular Weight416.48
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    GNE-955 [1527523-39-2]
  • Delivery Days Customer
    86
  • CAS Number
    1527523-39-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    GNE-955
  • Molecular Formula
    C22H24N8O
  • Molecular Weight
    416.48
  • Scientific Description
    GNE-955 is a potent and orally active inhibitor of pan Pim kinase, with inhibition constants (Kis) of 0.018 nM, 0.11 nM, and 0.08 nM for Pim1, Pim2, and Pim3, respectively.
  • Shelf life instruction
    3 years
  • SMILES
    O(C)C=1C(=NC(N2C=3C(C=N2)=CN=C(C3)C4=NC(C)=CN=C4)=CC1)N5C[C@@H](N)CCC5
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Wang X, et al. Discovery of 5-Azaindazole (GNE-955) as a Potent Pan-Pim Inhibitor with Optimized Bioavailability. J Med Chem. 2017 May 25;60(10):4458-4473.
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