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ProductsBack/GNE684 [2438637-64-8]
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GNE684 [2438637-64-8]

Research Use Only
T11442
TargetMol Chemicals
Molecular Weight432.48
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Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    GNE684 [2438637-64-8]
  • Delivery Days Customer
    114
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    GNE684
  • Molecular Formula
    C23H24N6O3
  • Molecular Weight
    432.48
  • Scientific Description
    GNE684 is a potent inhibitor of receptor interacting protein 1 (RIP1) with average Ki app values of 21 nM for human, 189 nM for mouse, and 691 nM for rat RIP1, respectively [1].
  • Shelf life instruction
    3 years
  • SMILES
    C(N[C@@H]1C(=O)N(C)C=2C(CC1)=CC(OC)=NC2)(=O)C3=NN4[C@@H](CCC4=N3)C5=CC=CC=C5
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Patel S, et al. RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases. Cell Death Differ. 2019 May 17.
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