GNF-7

MedChem Express

GNF-7 [839706-07-9]

10

839706-07-9

Research Use Only

99.70

C28H24F3N7O2

547.53

GNF-7 is a multikinase inhibitor. GNF-7 is a Bcr-Abl inhibitor, with IC 50 s of 133 nM and 61 nM for Bcr-Abl WT and Bcr-Abl T315I , respectively. GNF-7 also possesses inhibitory activity against both ACK1 (activated CDC42 kinase 1) and GCK (germinal center kinase) with IC 50 s of 25 nM and 8 nM, respectively. GNF-7 can be used for the research of hematologic malignancies [1] [2] [3] .

O=C(NC1=CC=C(C)C(N2CC3=CN=C(NC4=CC=C(C)N=C4)N=C3N(C)C2=O)=C1)C5=CC=CC(C(F)(F)F)=C5

-20°C,2°C to 8°C

12352200