GNF2133 [2561414-56-8]
HY-142295
CAS Number2561414-56-8
Product group Chemicals
Estimated Purity98.49
Molecular Weight434.53
Overview
- SupplierMedChem Express
- Product NameGNF2133 [2561414-56-8]
- Delivery Days Customer10
- CAS Number2561414-56-8
- CertificationResearch Use Only
- Estimated Purity98.49
- Molecular FormulaC24H30N6O2
- Molecular Weight434.53
- Scientific DescriptionGNF2133 is a potent, selective and orally active DYRK1A inhibitor with IC50s of 0.0062, >50 microM for DYRK1A and GSK3beta, respectively. GNF2133 shows good proliferation potency and efficacy on rat and human primary beta-cell. GNF2133 significantly improves glucose disposal capacity and increases insulin secretion. GNF2133 has the potential for the research of type 1 diabetes[1].
- SMILESCCN1CCN(CC1)C(NC2=NC=CC(C3=CN(C4=CN=CC=C34)C5CCOCC5)=C2)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200