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GNF2133 (hydrochloride)

Research Use Only
HY-142295A
MedChem Express
Molecular Weight470.99
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Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    GNF2133 (hydrochloride)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Molecular Formula
    C24H31ClN6O2
  • Molecular Weight
    470.99
  • Scientific Description
    GNF2133 hydrochloride is a potent, selective and orally active DYRK1A inhibitor with IC50s of 0.0062, >50 microM for DYRK1A and GSK3beta, respectively. GNF2133 hydrochloride shows good proliferation potency and efficacy on rat and human primary beta-cell. GNF2133 hydrochloride significantly improves glucose disposal capacity and increases insulin secretion. GNF2133 hydrochloride has the potential for the research of type 1 diabetes[1].
  • SMILES
    O=C(N1CCN(CC1)CC)NC2=NC=CC(C3=CN(C4CCOCC4)C5=C3C=CN=C5)=C2.Cl
  • UNSPSC
    12352200