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ProductsBack/GnRH-Receptor / LH-RH Receptor(GNRHR/2982R), CF594 conjugate, 0.1mg/mL [26628-22-8]
GnRH-Receptor / LH-RH Receptor(GNRHR/2982R), CF594 conjugate, 0.1mg/mL [26628-22-8]

GnRH-Receptor / LH-RH Receptor(GNRHR/2982R), CF594 conjugate, 0.1mg/mL [26628-22-8]

Research Use Only
BNC942982
Biotium
ReactivityBovine, Human, Rabbit
Product group Antibodies
TargetGNRHR
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Overview

  • Supplier
    Biotium
  • Product Name
    GnRH-Receptor / LH-RH Receptor(GNRHR/2982R), CF594 conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    GNRHR/2982R
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID2798
  • Target name
    GNRHR
  • Target description
    gonadotropin releasing hormone receptor
  • Target synonyms
    gnRH receptor; gnRH-R; GNRHR1; gonadotropin-releasing hormone (type 1) receptor 1; gonadotropin-releasing hormone receptor; GRHR; HH7; leutinizing hormone releasing horomone receptor; leutinizing-releasing hormone receptor; LHRHR; LRHR; luliberin receptor; type I GnRH receptor
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP22888
  • Protein Name
    Lutropin-choriogonadotropic hormone receptor
  • Scientific Description
    Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR). Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulating hormone (FSH). GnRH influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of GnRH on breast carcinoma correlates in part to the degree of tumor differentiation. GnRH-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. GnRH is present in luteal and granulosa cells as well as in ovarian cell membrane preparations. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Rabbit
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203