Non-transfected (–) and transfected (+) boiled and unboiled 293T whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with GnRHR antibody [HL2638] (GTX639094) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
![GnRHR antibody [HL2638] detects GnRHR protein at cell membrane by immunohistochemical analysis. Sample: Paraffin-embedded human PC-3 xenograft. GnRHR stained by GnRHR antibody [HL2638] (GTX639094) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX639094/GTX639094_T-45187_20231106_IHC-P_23111422_397.webp "GnRHR antibody [HL2638] detects GnRHR protein at cell membrane by immunohistochemical analysis. Sample: Paraffin-embedded human PC-3 xenograft. GnRHR stained by GnRHR antibody [HL2638] (GTX639094) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min")
![GnRHR antibody [HL2638] detects GnRHR protein by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. GnRHR stained by GnRHR antibody [HL2638] (GTX639094) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX639094/GTX639094_T-45187_20231103_IHC-P_M_23120519_824.webp "GnRHR antibody [HL2638] detects GnRHR protein by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. GnRHR stained by GnRHR antibody [HL2638] (GTX639094) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min")
![Boiled and unboiled PC-3 whole cell and membrane extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with GnRHR antibody [HL2638] (GTX639094) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. (WCE: whole cell extract; ME: membrane extract)](https://www.genetex.com/upload/website/prouct_img/normal/GTX639094/GTX639094_45299_20240126_WB_Fraction_24013018_158.webp "Boiled and unboiled PC-3 whole cell and membrane extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with GnRHR antibody [HL2638] (GTX639094) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. (WCE: whole cell extract; ME: membrane extract)")
![Non-transfected (–) and transfected (+) unboiled PC-3 whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with GnRHR antibody [HL2638] (GTX639094) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX639094/GTX639094_45299_20240202_WB_shRNA_watermark_24021917_540.webp "Non-transfected (–) and transfected (+) unboiled PC-3 whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with GnRHR antibody [HL2638] (GTX639094) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.")
![GnRHR antibody [HL2638] detects GnRHR protein at cell membrane by immunohistochemical analysis. Sample: Paraffin-embedded PC-3 xenograft. GnRHR stained by GnRHR antibody [HL2638] (GTX639094) diluted at 1:200 and competitor's antibody (19950-1-AP) diluted at 1:200. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min *Competitor's antibody is not affiliated with GeneTex and does not endorse this product.](https://www.genetex.com/upload/website/prouct_img/normal/GTX639094/GTX639094_45299_20240301_IHC-P_competitor_24030600_229.webp "GnRHR antibody [HL2638] detects GnRHR protein at cell membrane by immunohistochemical analysis. Sample: Paraffin-embedded PC-3 xenograft. GnRHR stained by GnRHR antibody [HL2638] (GTX639094) diluted at 1:200 and competitor's antibody (19950-1-AP) diluted at 1:200. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min *Competitor's antibody is not affiliated with GeneTex and does not endorse this product.")
Non-transfected (–) and transfected (+) boiled and unboiled 293T whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with GnRHR antibody [HL2638] (GTX639094) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
GnRHR antibody [HL2638]
GTX639094
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetGNRHR
Overview
- SupplierGeneTex
- Product NameGnRHR antibody [HL2638]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHL2638
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2798
- Target nameGNRHR
- Target descriptiongonadotropin releasing hormone receptor
- Target synonymsGNRHR1, GRHR, HH7, LHRHR, LRHR, gonadotropin-releasing hormone receptor, gnRH receptor, gnRH-R, gonadotropin-releasing hormone (type 1) receptor 1, leutinizing hormone releasing horomone receptor, leutinizing-releasing hormone receptor, luliberin receptor, type I GnRH receptor
- HostRabbit
- IsotypeIgG
- Protein IDP30968
- Protein NameGonadotropin-releasing hormone receptor
- Scientific DescriptionThis gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5 region and multiple polyA signals in the 3 region have been identified for this gene. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
Datasheet
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