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Golden Syrian Hamster IgG isotype control

GTX35005
GeneTex
ApplicationsFlow Cytometry, ELISA
Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    Golden Syrian Hamster IgG isotype control
  • Delivery Days Customer
    9
  • Application Supplier Note
    Use at a concentration/dilution equivalent to that of your experimental primary antibody.
  • Applications
    Flow Cytometry, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Host
    Hamster
  • Isotype
    IgG
  • Scientific Description
    Inclusion of an appropriate isotype control is essential for the proper interpretation of experimental results. Because isotype control antibodies have no relevant specificity, they enable the researcher to distinguish non-specific background binding from antigen-specific antibody binding. Non-specific binding of primary antibodies may occur due to either binding of antibody to Fc receptors or non-specific interactions with cellular proteins, lipids, or carbohydrates. Additionally, autofluorescence or endogenous enzyme activity in target cells may give a false positive that could be misinterpreted as antibody binding. These factors vary by target cell type and the isotype of the primary antibody. Therefore, the primary antibody used should be matched to an isotype control of identical species and isotype (including both heavy and light chains).
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Premacular Cells as Source of Neurotrophic Factors in Idiopathic Macular Holes. Vogt D et al., 2020 Nov, Curr Eye Res
    Read more
  • CD28 Promotes Plasma Cell Survival, Sustained Antibody Responses, and BLIMP-1 Upregulation through Its Distal PYAP Proline Motif. Rozanski CH et al., 2015 May 15, J Immunol
    Read more