Golden Syrian Hamster IgG isotype control
GTX35005
Overview
- SupplierGeneTex
- Product NameGolden Syrian Hamster IgG isotype control
- Delivery Days Customer9
- Application Supplier NoteUse at a concentration/dilution equivalent to that of your experimental primary antibody.
- ApplicationsFlow Cytometry, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- HostHamster
- IsotypeIgG
- Scientific DescriptionInclusion of an appropriate isotype control is essential for the proper interpretation of experimental results. Because isotype control antibodies have no relevant specificity, they enable the researcher to distinguish non-specific background binding from antigen-specific antibody binding. Non-specific binding of primary antibodies may occur due to either binding of antibody to Fc receptors or non-specific interactions with cellular proteins, lipids, or carbohydrates. Additionally, autofluorescence or endogenous enzyme activity in target cells may give a false positive that could be misinterpreted as antibody binding. These factors vary by target cell type and the isotype of the primary antibody. Therefore, the primary antibody used should be matched to an isotype control of identical species and isotype (including both heavy and light chains).
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Premacular Cells as Source of Neurotrophic Factors in Idiopathic Macular Holes. Vogt D et al., 2020 Nov, Curr Eye ResRead more
- CD28 Promotes Plasma Cell Survival, Sustained Antibody Responses, and BLIMP-1 Upregulation through Its Distal PYAP Proline Motif. Rozanski CH et al., 2015 May 15, J ImmunolRead more