Gossypol
S6852
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameGossypol
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionGossypol (BL 193) is an orally-active polyphenol isolated from cotton seeds and roots. Gossypol is a potent inhibitor of 5alfa-reductase 1 and 3alfa-hydroxysteroid dehydrogenase with IC50 of 3.33 muM and 0.52 muM in cell-free assay, respectively. Gossypol also inhibits the binding of BH3 peptide to Bcl protein with IC50 of 0.4 muM and 10 muM for Bcl-XL and Bcl-2, respectively. Gossypol induces apoptosis and cell growth inhibition in various cancer cells.
- UNSPSC12352200
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