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gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF640R conjugate, 0.1mg/mL [26628-22-8]

gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF640R conjugate, 0.1mg/mL [26628-22-8]

BNC401825
Biotium
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Rabbit
TargetPMEL
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Overview

  • Supplier
    Biotium
  • Product Name
    gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF640R conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    PMEL/1825R
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID6490
  • Target name
    PMEL
  • Target description
    premelanosome protein
  • Target synonyms
    D12S53E; gp100; ME20; ME20M; ME20-M; melanocyte protein mel 17; melanocyte protein PMEL; melanocyte protein Pmel 17; melanocytes lineage-specific antigen GP100; melanoma-associated ME20 antigen; melanosomal matrix protein17; P1; P100; PMEL17; SI; SIL; SILV; silver locus protein homolog; silver, mouse, homolog of
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP40967
  • Protein Name
    Melanocyte protein PMEL
  • Scientific Description
    Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Rabbit
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203