gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker)(HMB45 + PMEL/783), CF405S conjugate, 0.1mg/mL [26628-22-8]
BNC040951
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetPMEL
Overview
- SupplierBiotium
- Product Namegp100 / Melanosome / PMEL17 / SILV (Melanoma Marker)(HMB45 + PMEL/783), CF405S conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHMB45 PMEL/783
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID6490
- Target namePMEL
- Target descriptionpremelanosome protein
- Target synonymsD12S53E; gp100; ME20; ME20M; ME20-M; melanocyte protein mel 17; melanocyte protein PMEL; melanocyte protein Pmel 17; melanocytes lineage-specific antigen GP100; melanoma-associated ME20 antigen; melanosomal matrix protein17; P1; P100; PMEL17; SI; SIL; SILV; silver locus protein homolog; silver, mouse, homolog of
- HostMouse
- IsotypeIgG1
- Protein IDP40967
- Protein NameMelanocyte protein PMEL
- Scientific DescriptionBy immunohistochemistry, this antibody specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. This MAb stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignant melanoma. This MAb also stains Angiomyolipoma (PEComa).
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203