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gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker)(HMB45 + PMEL/783), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC040951
Biotium
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetPMEL
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Overview

  • Supplier
    Biotium
  • Product Name
    gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker)(HMB45 + PMEL/783), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    HMB45 PMEL/783
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID6490
  • Target name
    PMEL
  • Target description
    premelanosome protein
  • Target synonyms
    D12S53E; gp100; ME20; ME20M; ME20-M; melanocyte protein mel 17; melanocyte protein PMEL; melanocyte protein Pmel 17; melanocytes lineage-specific antigen GP100; melanoma-associated ME20 antigen; melanosomal matrix protein17; P1; P100; PMEL17; SI; SIL; SILV; silver locus protein homolog; silver, mouse, homolog of
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP40967
  • Protein Name
    Melanocyte protein PMEL
  • Scientific Description
    By immunohistochemistry, this antibody specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. This MAb stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignant melanoma. This MAb also stains Angiomyolipoma (PEComa).
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203