GP130-IN-1

MedChem Express

GP130-IN-1

9

Research Use Only

C21H10F5NO3

419.30

GP130-IN-1 (compound 49) is a potent GP130 inhibitor with significant in vitro antitumor activity and higher selectivity than Bazedoxifene (HY-A0031). GP130-IN-1 induces ultrastructural changes in cells, causing cell cycle arrest in the G0/G1 phase in a time-dependent manner and triggering apoptosis and autophagy. GP130-IN-1 can be used in the study of triple-negative breast cancer[1].

O=C(N1C(C2=CC=C(O)C=C2)=CC3=C1C=CC(O)=C3)C4=C(F)C(F)=C(F)C(F)=C4F

12352200