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IHC-P analysis of mouse brain tissue using GTX85034 GPAM antibody. Working concentration : 5 microg/ml
IHC-P analysis of mouse brain tissue using GTX85034 GPAM antibody. Working concentration : 5 microg/ml
IHC-P analysis of mouse brain tissue using GTX85034 GPAM antibody. Working concentration : 5 microg/ml

GPAM antibody

GTX85034
GeneTex
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetGPAM
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Overview

  • Supplier
    GeneTex
  • Product Name
    GPAM antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1 - 2 microg/mL. IHC-P: 2.5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID57678
  • Target name
    GPAM
  • Target description
    glycerol-3-phosphate acyltransferase, mitochondrial
  • Target synonyms
    glycerol-3-phosphate acyltransferase 1, mitochondrial; GPAT; GPAT1; GPAT-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9HCL2
  • Protein Name
    Glycerol-3-phosphate acyltransferase 1, mitochondrial
  • Scientific Description
    Glycerol-3-phosphate acyltransferase 1 (GPAT1), one of four known GPAT isoforms, is located on the mitochondrial outer membrane, allowing reciprocal regulation with carnitine palmitoyltransferase-1. It is thought to be critical for the development of hepatic steatosis; steatosis triggered by GPAT1 overexpression leads to hepatic and possibly peripheral insulin resistance. GPAT1 is transcriptionally upregulated by insulin and sterol regulatory element binding protein (SREBP-1) and downregulated by AMP-activated protein kinase. Mice deficient in GPAT1 exhibit decreased triacylglycerol (TAG) in cardiomyocytes even in high-fat diets, suggesting that GPAT1 contributes significantly to TAG accumulation in heart tissue during lipogenic or high fat diets. At least two isoforms of GPAT1 are known to exist.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

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