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GPI-1046

HY-124619
MedChem Express
CAS Number186452-09-5
DownloadMSDS
Product group Chemicals
Estimated Purity99.79
Molecular Weight360.45
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Overview

  • Supplier
    MedChem Express
  • Product Name
    GPI-1046 [186452-09-5]
  • Delivery Days Customer
    10
  • CAS Number
    186452-09-5
  • Certification
    Research Use Only
  • Estimated Purity
    99.79
  • Molecular Formula
    C20H28N2O4
  • Molecular Weight
    360.45
  • Scientific Description
    GPI-1046 is an orally active, antibiotic-free immunophilin ligand that reduces ethanol intake by upregulating glutamate transporter 1 (GLT1) in the prefrontal cortex (PFC) and nucleus accumbens core (NAc-core). GPI-1046 improves human immunodeficiency virus (HIV)-associated sensory neuropathy (HIV-SN) by attenuating store-operated calcium (SOC) entry. GPI-1046 has neuroprotective activity[1][2][3].
  • SMILES
    O=C(OCCCC1=CC=CN=C1)[C@H]2N(C(C(C(C)(C)CC)=O)=O)CCC2
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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