GPR81 agonist 1

MedChem Express

GPR81 agonist 1 [1620992-67-7]

10

1620992-67-7

Research Use Only

99.73

C22H30N4O2S2

446.63

GPR81 agonist 1 is a potent and highly selective GPR81 agonist, with EC 50 s of 58 nM and 50 nM for human and mouse GPR81, respectively. GPR81 agonist 1 inhibits lipolysis in differentiated 3T3-L1 adipocytes. GPR81 agonist 1 suppresses lipolysis in mice without cutaneous flushing. GPR81 agonist 1 displays remarkable selectivity for GPR81 over GPR109a [1] .

O=C([C@H]1CC[C@H](C)CC1)NC2=NC(C3=CC=CS3)=C(CC(N4CCN(C)CC4)=O)S2

-20°C,2°C to 8°C

12352200