GPS491

MedChem Express

GPS491 [2655502-29-5]

10

2655502-29-5

Research Use Only

C13H5F6N3OS2

397.32

GPS491 ( EC 50 = 0.47 microM) suppresses expression of the HIV-1 structural protein Gag and alters HIV-1 RNA accumulation, decreasing the abundance of RNAs encoding the structural proteins while increasing levels of viral RNAs encoding the regulatory proteins.

O=C(NC1=NC(C=CC(C(F)(F)F)=C2)=C2S1)C3=CN=C(C(F)(F)F)S3

12352200