GPT2 Polyclonal Antibody
RD219961A
TargetGPT2
Product group Antibodies
Overview
- SupplierReddot Biotech
- Product NameGPT2 Polyclonal Antibody
- Delivery Days Customer5
- Concentration2.16 mg/ml
- Gene ID84706
- Target nameGPT2
- Target descriptionglutamic--pyruvic transaminase 2
- Target synonymsalanine aminotransferase 2; ALT2; glutamate pyruvate transaminase 2; glutamic pyruvate transaminase (alanine aminotransferase) 2; glutamic pyruvate transaminase 2; glutamic--alanine transaminase 2; GPT 2; MRT49; NEDSPM
- Scientific DescriptionThis gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants.
- Storage Instruction-20°C
- UNSPSC12352203