Western blot analysis of extracts from 3T3 cells (Lane 2), using GRIN2B (Ab-1303) antiobdy. The lane on the left is treated with synthesized peptide.
Western blot analysis of extracts from 3T3 cells (Lane 2), using GRIN2B (Ab-1303) antiobdy. The lane on the left is treated with synthesized peptide.
GRIN2B (Ab-1303) Antibody
CSB-PA149419
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetGRIN2B
Overview
- SupplierCusabio
- Product NameGRIN2B (Ab-1303) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID2904
- Target nameGRIN2B
- Target descriptionglutamate ionotropic receptor NMDA type subunit 2B
- Target synonymsDEE27; EIEE27; GluN2B; GluN2B(alt_5'UTR); glutamate [NMDA] receptor subunit epsilon-2; glutamate receptor ionotropic, NMDA 2B; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, N-methyl D-aspartate 2B; hNR3; MRD6; NMDAR2B; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 3; NR2B; NR3
- HostRabbit
- IsotypeIgG
- Protein IDQ13224
- Protein NameGlutamate receptor ionotropic, NMDA 2B
- Scientific DescriptionNMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death By similarity. Lasky L.A., J. Biol. Chem. 275:21477-21485(2000). Mandich P., Neurosci. Lett. 239:49-53(1997). Ajmar F., Genomics 22:216-218(1994).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203