GRK5-IN-4

MedChem Express

GRK5-IN-4

10

Research Use Only

C26H25N7O3

483.52

GRK5-IN-4 (Compound 16d, CCG-265328) is a potent and and selective covalent GRK5 (G protein-coupled receptor kinase 5) inhibitor, with an IC50 of 1.1 microM. GRK5-IN-4 shows 90-fold selectivity over GRK2. GRK5-IN-4 can be used for heart failure research.

O=C(NCC1=CC=C(C(OC)=C1)NC2=NC(NC3=C(C(NC)=O)C=CC=C3)=C4C=CNC4=N2)C#CC

See Manual

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