GRP78-IN-3 [2707510-30-1]

TargetMol Chemicals

GRP78-IN-3 [2707510-30-1]

4

Chemical

Research Use Only

GRP78-IN-3

99.11%

C17H18N4O2S

342.42

GRP78-IN-3, a potent small-molecule-competitive inhibitor of Hsp70 substrate binding and is a selective Grp78 (HSPA5) inhibitor with an IC50 of 0.59 microM. GRP78-IN-3 is 7-fold selective for HspA5 compared to HspA9 (IC50 of 4.3 microM) and >20-fold selective for HspA5 compared to HspA2 (IC50 of 13.9 microM).

3 years

C(N[C@H](C(NC1=NC=CS1)=O)[C@H](C)C)(=O)C2=CC=3C(N2)=CC=CC3

-20°C

51202000