GRP78-IN-3

MedChem Express

GRP78-IN-3

10

Research Use Only

99.98

C17H18N4O2S

342.42

GRP78-IN-3 (Compound 8) is a selective Grp78 (HSPA5) inhibitor with an IC50 of 0.59 microM. GRP78-IN-3 is 7-fold selective for HspA5 compared to HspA9 (IC50 of 4.3 microM) and >20-fold selective for HspA5 compared to HspA2 (IC50 of 13.9 microM)[1].

O=C(C1=CC2=C(N1)C=CC=C2)N[C@H](C(NC3=NC=CS3)=O)C(C)C

-20°C

12352200