GRPR antagonist-1

TargetMol Chemicals

GRPR antagonist-1

114

Chemical

Research Use Only

GRPR antagonist-1

C29H33F3N4O4

558.59

GRPR antagonist-1 is a potent antagonist of the gastrin-releasing peptide receptor (GRPR) and displays cytotoxicity to certain cancer cells, including PC3 cells (IC50: 4.97 microM), Pan02 cells (IC50: 4.36 microM), and HGC-27 cells (IC50: 3.40 microM). It reduces Bcl-2 levels, increases Bax levels, inhibits HGC-27 cell viability, and induces apoptosis, thereby exhibiting anti-cancer effects.

3 years

-20°C

12352200