
IHC-P analysis of human lung, non-small cell carcinoma tissue using GTX13339 GRPR antibody. Antigen retrieval : Heat-induced antigen retrieval
GRPR antibody
GTX13339
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Equine, Human, Mammals, Monkey, Porcine, Rabbit
TargetGRPR
Overview
- SupplierGeneTex
- Product NameGRPR antibody
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 4 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2925
- Target nameGRPR
- Target descriptiongastrin releasing peptide receptor
- Target synonymsBB2; BB2R; bombesin receptor 2; BRS2; gastrin-releasing peptide receptor; GRP-preferring bombesin receptor; GRP-R
- HostRabbit
- IsotypeIgG
- Protein IDP30550
- Protein NameGastrin-releasing peptide receptor
- Scientific DescriptionGastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]
- ReactivityCanine, Equine, Human, Mammals, Monkey, Porcine, Rabbit
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203