GRPR Polyclonal Antibody

Reddot Biotech

GRPR Polyclonal Antibody

5

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

1.1 mg/ml

Unconjugated

GRPR

gastrin releasing peptide receptor

BB2, BB2R, BRS2, gastrin-releasing peptide receptor, GRP-R, GRP-preferring bombesin receptor, bombesin receptor 2

Rabbit

IgG

Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.

-20°C

12352203