GS-441524 HCl
T69657
CAS Number2378280-82-9
Product group Chemicals
Molecular Weight327.725
Overview
- SupplierTargetMol Chemicals
- Product NameGS-441524 HCl
- Delivery Days Customer65
- CAS Number2378280-82-9
- Category SupplierChemical
- Chemical NameGS-441524 HCl
- Molecular FormulaC12H14ClN5O4
- Molecular Weight327.725
- Scientific DescriptionGS-441524 is a potent inhibitor of feline infectious peritonitis (FIP) virus with an EC50 of 0.78 uM. GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies. GS-441524 is a molecular precursor to a pharmacologically active nucleoside triphosphate molecule. These analogs act as an alternative substrate and RNA-chain terminator of viral RNA dependent RNA polymerase. GS-441524 was non-toxic in feline cells at concentrations as high as 100 uM and effectively inhibited FIPV replication in cultured CRFK cells and in naturally infected feline peritoneal macrophages at concentrations as low as 1 uM. Note: GS-441524 is an active metabolite of Remdesivir.
- Shelf life instruction3 years
- Storage Instruction-20°
- UNSPSC12352200