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GS-443902

T5539
TargetMol Chemicals
CAS Number1355149-45-9
Product group Chemicals
Molecular Weight531.2
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    GS-443902
  • Delivery Days Customer
    1001
  • CAS Number
    1355149-45-9
  • Category Supplier
    Chemical
  • Chemical Name
    GS-443902
  • Molecular Formula
    C12H16N5O13P3
  • Molecular Weight
    531.2
  • Scientific Description
    Remdesivir triphosphate is a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp) with IC50s of 1.1 uM, 5 uM for RSV RdRp and HCV RdRp, respectively. GS-443902 is the active triphosphate metabolite of Remdesivir.
  • Shelf life instruction
    3 years
  • SMILES
    Nc1ncnn2c(ccc12)[C@@]1(O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O)C#N
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Pedersen N C , Perron M , Bannasch M , et al. Efficacy and safety of the nucleoside analog GS-441524 for treatment of cats with naturally occurring feline infectious peritonitis[J]. Journal of Feline Medicine & Surgery, 2019.