GS-9191 [859209-84-0]

TargetMol Chemicals

GS-9191 [859209-84-0]

4

Chemical

Research Use Only

GS-9191

98.28%

C37H51N8O6P

734.82

GS-9191 is a potent inhibitor of DNA polymerase alpha and beta , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , which penetrates the skin and is metabolized in the epithelium to an active nucleoside triphosphate analogue.GS-9191 has antiproliferative activity and reduces the size of papillomas in a dose-related manner.GS-9191 may be useful in the treatment of HPV-induced lesions.

3 years

C(COCP(N[C@@H](CC1=CC=CC=C1)C(OCC(C)C)=O)(N[C@@H](CC2=CC=CC=C2)C(OCC(C)C)=O)=O)N3C=4C(=C(NC5CC5)N=C(N)N4)N=C3

-20°C

12352200