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GSDMA Antibody, Biotin conjugated

Research Use Only
CSB-PA850415LD01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetGSDMA
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    Cusabio
  • Product Name
    GSDMA Antibody, Biotin conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Biotin
  • Gene ID284110
  • Target name
    GSDMA
  • Target description
    gasdermin A
  • Target synonyms
    FKSG9; gasdermin-1; gasdermin-A; GSDM; GSDM1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ96QA5
  • Protein Name
    Gasdermin-A
  • Scientific Description
    May promote pyroptosis (Probable). Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4,5)-bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity (PubMed:27281216). The physiological relevance of these observations is unknown (Probable).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203