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ProductsBack/GSK-2578215A [1285515-21-0]

GSK-2578215A [1285515-21-0]

G733400
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 1.018,00
100 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    GSK-2578215A [1285515-21-0]
  • Delivery Days Customer
    7
  • Estimated Purity
    ≥98%
  • Scientific Description
    Selective inhibitor of LRRK2.; GSK2578215A; Q641JSF42X; CHEMBL2204495;GSK257821A; AK174163; 2-(benzyloxy)-5-(2-fluoropyridin-4-yl)-N-(pyridin-3-yl)benzamide; Benzamide, 5-(2-fluoro-4-pyridinyl)-2-(phenylmethoxy)-N-3-pyridinyl-
  • Storage Instruction
    4°C
  • UNSPSC
    12352200

References

  • Reith A., Bamborough P., et al. GSK2578215A; a potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitor. Bioorg Med Chem Lett. 22(17):5625-9 (2012). PMID: 22863203. Saez-Atienzar S., Bonet-Ponce L., et al. The LRRK2 inhibitor GSK2578215A induces protective autophagy in SH-SY5Y cells: involvement of Drp-1-mediated mitochondrial fission and mitochondrial-derived ROS signaling. Cell Death Dis. 5:e1368 (2014). PMID: 25118928.