GSK-343

Biorbyt

GSK-343 [1346704-33-3]

16

1346704-33-3

Research Use Only

C31H39N7O2

541.6871

GSK343 is a potent and selective EZH2 inhibitor with IC50 of 4 nM, showing 60 fold selectivity against EZH1, and > 1000 fold selectivity against other histone methyltransferases.

O=C(C1C([H])=C(C([H])=C2C=1C([H])=NN2C([H])(C([H])([H])[H])C([H])([H])[H])C1C([H])=C([H])N=C(C=1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])N([H])C([H])([H])C1C(N([H])C(C([H])([H])[H])=C([H])C=1C([H])([H])C([H])([H])C([H])([H])[H])=

12352200