GSK163090

MedChem Express

GSK163090 [844903-58-8]

10

844903-58-8

Research Use Only

99.77

C25H29N5O

415.53

GSK163090 is a potent, selective and orally active 5-HT1A/1B/1D receptor antagonist with pKi values of 9.4/8.5/9.7, respectively. GSK163090 inhibits the functional activity of serotonin reuptake transporter (SerT) with a pKi value of 6.1. GSK163090 has antidepressant and anxiolytic activities[1].

O=C1NCCN1C2=CC=CC(CCN3CCN(C4=C5C=CC(C)=NC5=CC=C4)CC3)=C2

-20°C,2°C to 8°C

12352200