GSK172981 [1133705-99-3]

TargetMol Chemicals

GSK172981 [1133705-99-3]

999

Chemical

Research Use Only

GSK172981

C26H22FN3O

411.47

GSK172981 is a non-peptide tachykinin NK3 receptor antagonist with a high affinity for the recombinant human (PK (I) value 7.7) and native guinea pig (PK (I) value 7.8) tachykinin NK3 receptor. In vitro, the functional evaluation showed that GSK172981 was a competitive antagonist for the cloned human tachykinin NK(3) receptor (PA (2)=7.2). GSK172981 may be used to treat schizophrenia.

3 years

C(N[C@@H]([C@@H]1CC1)C2=CC=CC=C2)(=O)C=3C4=C(N=C(C3N)C5=CC(F)=CC=C5)C=CC=C4

-20°C

12352200