
ICC/IF analysis of methanol-fixed HeLa cells using GTX50090 GSK3 beta (phospho Ser9) antibody.
GSK3 beta (phospho Ser9) antibody

GTX50090
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetGSK3B
Overview
- SupplierGeneTex
- Product NameGSK3 beta (phospho Ser9) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000. ICC/IF: 1:100-1:200. IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID2932
- Target nameGSK3B
- Target descriptionglycogen synthase kinase 3 beta
- Target synonymsglycogen synthase kinase-3 beta; GSK-3 beta; serine/threonine-protein kinase GSK3B
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Protein IDP49841
- Protein NameGlycogen synthase kinase-3 beta
- Scientific DescriptionThe protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- The Long-Term DEHP Exposure Confers Multidrug Resistance of Triple-Negative Breast Cancer Cells through ABC Transporters and Intracellular ROS. Jadhao M et al., 2021 Jun 11, Antioxidants (Basel)Read more
- Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3beta-beta-Catenin and XIAP-Survivin Pathways. Chang YX et al., 2020 Dec 21, Cancers (Basel)Read more
- Sclareol ameliorated ERCC1-mediated cisplatin resistance in A549 human lung adenocarcinoma cells and a murine xenograft tumor model by suppressing AKT-GSK3beta-AP1/Snail and JNK-AP1 pathways. Pan CH et al., 2020 Dec 1, Chem Biol InteractRead more
- Pnma5 is essential to the progression of meiosis in mouse oocytes through a chain of phosphorylation. Zhang XL et al., 2017 Nov 14, OncotargetRead more