Western blot analysis of extracts from HL60, HT29 and 293 cells using GSK3-alpha;/beta(Ab-279/216) Antibody.
Western blot analysis of extracts from HL60, HT29 and 293 cells using GSK3-alpha;/beta(Ab-279/216) Antibody.
GSK3A/GSK3B (Ab-279/216) Antibody
CSB-PA255909
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetGSK3A
Overview
- SupplierCusabio
- Product NameGSK3A/GSK3B (Ab-279/216) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID2931
- Target nameGSK3A
- Target descriptionglycogen synthase kinase 3 alpha
- Target synonymsglycogen synthase kinase-3 alpha; GSK-3 alpha; serine/threonine-protein kinase GSK3A
- HostRabbit
- IsotypeIgG
- Protein IDP49840
- Protein NameGlycogen synthase kinase-3 alpha
- Scientific DescriptionParticipates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Chin PC, et al. Brain Res Mol Brain Res 2005 Jun 13; 137(1-2): 193-201 Takahashi-Yanaga F, et al. Biochem Biophys Res Commun 2004 Apr 02; 316(2): 411-415 Fan G, et al. J Biol Chem 2003 Dec 26; 278(52): 52432-52436 Liao X, et al. Mol Cancer Ther 2003 Nov; 2(11): 1215-1222
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203