Western blot analysis of extracts from A2780 and HT29 cells using GSK3b(Ab-9) Antibody.
Western blot analysis of extracts from A2780 and HT29 cells using GSK3b(Ab-9) Antibody.
GSK3B (Ab-9) Antibody
CSB-PA120951
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGSK3B
Overview
- SupplierCusabio
- Product NameGSK3B (Ab-9) Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID2932
- Target nameGSK3B
- Target descriptionglycogen synthase kinase 3 beta
- Target synonymsglycogen synthase kinase-3 beta; GSK-3 beta; serine/threonine-protein kinase GSK3B
- HostRabbit
- IsotypeIgG
- Protein IDP49841
- Protein NameGlycogen synthase kinase-3 beta
- Scientific DescriptionParticipates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Fan G, et al. (2003) J Biol Chem. 278(52): 52432-52436.Barry FA, et al. (2003) FEBS Lett. 553(1-2): 173-178.Welsh, et al. (1996) Trends Cell Biol. 6: 274-279.Srivastava A K, et al. (1998) Mol Cell Biochem. 182: 135-141.Cross D. A, et al. (1995) Nature. 378: 785-789.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203