GSK563 [1983928-04-6]

TargetMol Chemicals

GSK563 [1983928-04-6]

72

1983928-04-6

Chemical

Research Use Only

GSK563

C16H22O2

246.34

GSK563 is a potent GVIA iPLA2 inhibitor (XI(50) 0.0000021, IC50 1 nM). GSK563 is 22 000 times more active against GVIA iPLA2 than GIVA cPLA2. It was found to reduce beta-cell apoptosis induced by proinflammatory cytokines, raising the possibility that it can be beneficial in countering autoimmune diseases, such as type 1 diabetes.

3 years

C(CC)C1C(CCCCC2=CC=CC=C2)C(=O)O1

-20°C

12352200