GSK575594A
HY-111161
Molecular Weight471.52
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameGSK575594A
- Delivery Days Customer9
- CertificationResearch Use Only
- Molecular FormulaC24H23F2N3O3S
- Molecular Weight471.52
- Scientific DescriptionGSK575594A is a modulator of the nicotinic acetylcholine receptor ( nAChR ) in Ascaris suum . GSK575594A enhances muscle contractions induced by acetylcholine (ACh) by binding to the allosteric binding site between subunits within the transmembrane domain of nAChR . At a concentration of 3 microM, GSK575594A significantly increased the contraction induced by ACh in Ascaris suum ( E max increased from 1.19 g to 1.51 g). GSK575594A may be used in research within the field of antiparasitic studies [1] .
- SMILESO=C(N1CCN(C2=CC=C(N)C=C2F)CC1)C3=CC(S(=O)(C)=O)=CC=C3C4=CC=C(F)C=C4
- UNSPSC12352200