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CgoaEGY7SuSEJ8K-AAAAALpOp6Q133.png
CgoaEGY7SuSEJ8K-AAAAALpOp6Q133.png
CgoaEGY7SuSEJ8K-AAAAALpOp6Q133.png

GSK854

T24115
TargetMol Chemicals
CAS Number1316059-00-3
Product group Chemicals
Molecular Weight482.96
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    GSK854
  • Delivery Days Customer
    9
  • CAS Number
    1316059-00-3
  • Category Supplier
    Chemical
  • Chemical Name
    GSK854
  • Molecular Formula
    C18H19ClN6O4S2
  • Molecular Weight
    482.96
  • Scientific Description
    GSK854 is a highly selective and potent inhibitor of troponin I interacting kinase (TNNI3K) that inhibits myocardial infarction-injured cellular pyroptosis and apoptosis in mice, which may limit oxidative stress, injury, and adverse remodeling in the ischemic heart.
  • Shelf life instruction
    3 years
  • SMILES
    N(C1=C(S(CC)(=O)=O)C=CC(S(NC)(=O)=O)=C1)C=2C=C(NC3=CC=C(Cl)C=N3)N=CN2
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Philp J, et al. 4,6-Diaminopyrimidines as Highly Preferred Troponin I-Interacting Kinase (TNNI3K) Inhibitors. J Med Chem. 2018;61(7):3076-3088.
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